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In postindustrial societies, overeating, inactivity, and obesity<SUP> </SUP>have emerged as new challenges in public health.<A HREF="#R1"><SUP>1</SUP></A><SUP>,</SUP><A HREF="#R2"><SUP>2</SUP></A> Considerable<SUP> </SUP>effort is now being devoted to determining the pathophysiologic<SUP> </SUP>consequences of overeating. Several lines of evidence suggest<SUP> </SUP>that caloric intake influences the rate of aging and the onset<SUP> </SUP>of associated diseases in animals and, possibly, humans.<A HREF="#R3"><SUP>3</SUP></A><SUP>,</SUP><A HREF="#R4"><SUP>4</SUP></A><SUP>,</SUP><A HREF="#R5"><SUP>5</SUP></A><SUP> </SUP><P>


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